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Broad-spectrum -lactams for treating experimental peritonitis in mice due to Escherichia coli producing plasmid-encoded cephalosporinases
Author(s) -
Sophie Vimont,
Dominique Aubert,
JeanXavier Mazoit,
Laurent Poirel,
Patrice Nordmann
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm317
Subject(s) - cefepime , piperacillin , ceftazidime , imipenem , microbiology and biotechnology , tazobactam , piperacillin/tazobactam , escherichia coli , peritonitis , plasmid , medicine , biology , antibiotics , antibiotic resistance , bacteria , pseudomonas aeruginosa , surgery , dna , biochemistry , genetics , gene
To investigate the correlation between in vitro activity and in vivo efficacy of broad-spectrum beta-lactams for treating experimental infections due to Escherichia coli expressing two types of plasmid-mediated AmpC-type beta-lactamases, LAT-1 and FOX-1.

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