Open AccessIn vivo studies on the antileishmanial activity of buparvaquone and its prodrugs
Author(s) -
T. Garnier,
Antti Mäntylä,
Teea T Järvinen,
Judy Lawrence,
Marc B. Brown,
S. L. Croft
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm303
Subject(s) - prodrug , pharmacology , visceral leishmaniasis , in vivo , leishmania donovani , medicine , cutaneous leishmaniasis , drug , leishmaniasis , immunology , biology , microbiology and biotechnology
The efficacy of different formulations of the naphthoquinone buparvaquone and two phosphate prodrugs in in vivo models of both visceral and cutaneous leishmaniasis is described.
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