Open AccessSelection of quinolone resistance in Streptococcus pneumoniae exposed in vitro to subinhibitory drug concentrations
Author(s) -
Laëtitia Avrain,
Mark I. Garvey,
Narcisa Mesaros,
Youri Glupczynski,
MariePaule MingeotLeclercq,
Laura J. V. Piddock,
Paul M. Tulkens,
R. Vanhoof,
Françoise Van Bambeke
Publication year - 2007
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm292
Subject(s) - moxifloxacin , levofloxacin , microbiology and biotechnology , efflux , quinolone , ciprofloxacin , streptococcus pneumoniae , antibacterial agent , biology , sparfloxacin , ofloxacin , antibiotics , genetics
Does exposure to subinhibitory concentrations of quinolones favour overexpression of efflux pumps or selection of target site mutations?