Macrolide-resistant Staphylococcus aureus colonization in cystic fibrosis patients: is there transmission to household contacts?
Author(s) -
Gerdien A. TramperStranders,
Cornelis K. van der Ent,
Susan A. M. Gerritsen,
André Fleer,
Jan L. L. Kimpen,
Tom F.W. Wolfs
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm235
Subject(s) - staphylococcus aureus , azithromycin , colonization , cystic fibrosis , microbiology and biotechnology , transmission (telecommunications) , methicillin resistant staphylococcus aureus , micrococcaceae , staphylococcal infections , medicine , macrolide antibiotics , antibacterial agent , antibiotics , biology , bacteria , erythromycin , engineering , genetics , electrical engineering
Patients with cystic fibrosis (CF) are frequently colonized by macrolide-resistant Staphylococcus aureus, a result of maintenance macrolide therapy. As transmission of S. aureus between household contacts is common, we examined the prevalence of macrolide-resistant S. aureus colonization in CF patients on maintenance azithromycin therapy and their household contacts and compared this with the S. aureus macrolide resistance prevalence in the community.
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