Tamoxifen is effective against Leishmania and induces a rapid alkalinization of parasitophorous vacuoles harbouring Leishmania (Leishmania) amazonensis amastigotes | Zendy

Danilo C. Miguel | Zendy; Jenicer K. U. YokoyamaYasunaka | Zendy; Walter K. Andreoli | Zendy; Renato A. Mortara | Zendy; Sílvia Reni Bortolin Uliana | Zendy

Open Access

Tamoxifen is effective against Leishmania and induces a rapid alkalinization of parasitophorous vacuoles harbouring Leishmania (Leishmania) amazonensis amastigotes

Author(s) -

Danilo C. Miguel,

Jenicer K. U. YokoyamaYasunaka,

Walter K. Andreoli,

Renato A. Mortara,

Sílvia Reni Bortolin Uliana

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm219

Subject(s) - amastigote , leishmania , kinetoplastida , vacuole , leishmania major , tamoxifen , biology , leishmaniasis , microbiology and biotechnology , leishmania mexicana , immunology , protozoal disease , parasite hosting , genetics , cytoplasm , world wide web , computer science , malaria , cancer , breast cancer

This study was performed to investigate the activity of tamoxifen, an antioestrogen widely used in the treatment of breast cancer, against Leishmania.

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