Open AccessGatifloxacin in combination with rifampicin in a murine tuberculosis model
Author(s) -
Michael H. Cynamon,
Mary Sklaney,
Carolyn Shoen
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm200
Subject(s) - gatifloxacin , rifampicin , tuberculosis , medicine , microbiology and biotechnology , antibacterial agent , virology , antibiotics , biology , pathology , levofloxacin
Gatifloxacin previously demonstrated good in vitro and in vivo activities against Mycobacterium tuberculosis. Several regimens of gatifloxacin in combination with rifampicin were compared with isoniazid plus rifampicin in a mouse tuberculosis model.
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