Emergence of hepatitis B virus quasispecies with lower susceptibility to nucleos(t)ide analogues during lamivudine treatment | Zendy

F. Moriconi | Zendy; P. Colombatto | Zendy; B. Coco | Zendy; P. Ciccorossi | Zendy; Filippo Oliveri | Zendy; Diego Flichman | Zendy; A.M. Maina | Zendy; Rodolfo Sacco | Zendy; Ferruccio Bonino | Zendy; Maurizia Rossana Brunetto | Zendy

Open Access

Emergence of hepatitis B virus quasispecies with lower susceptibility to nucleos(t)ide analogues during lamivudine treatment

Author(s) -

F. Moriconi,

P. Colombatto,

B. Coco,

P. Ciccorossi,

Filippo Oliveri,

Diego Flichman,

A.M. Maina,

Rodolfo Sacco,

Ferruccio Bonino,

Maurizia Rossana Brunetto

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm187

Subject(s) - lamivudine , adefovir , virology , viral quasispecies , reverse transcriptase , hepatitis b virus , virus , hepatitis b , medicine , chronic hepatitis , reverse transcriptase inhibitor , biology , viral disease , hepatitis c virus , polymerase chain reaction , gene , genetics , sida

We studied the impact of hepatitis B virus (HBV) polymerase/reverse transcriptase (Pol/Rt) heterogeneity on adefovir rescue therapy in 34 consecutive chronic hepatitis B patients with viral breakthrough during lamivudine monotherapy.

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