A highly carbapenem-resistant Pseudomonas aeruginosa isolate with a novel blaVIM-4/blaP1b integron overexpresses two efflux pumps and lacks OprD | Zendy

Maria Maniati | Zendy; Alexandros Ikonomidis | Zendy; Paraskevi Mantzana | Zendy; Alexandros Daponte | Zendy; Antonios N. Maniatis | Zendy; Spyros Pournaras | Zendy

Open Access

A highly carbapenem-resistant Pseudomonas aeruginosa isolate with a novel blaVIM-4/blaP1b integron overexpresses two efflux pumps and lacks OprD

Author(s) -

Maria Maniati,

Alexandros Ikonomidis,

Paraskevi Mantzana,

Alexandros Daponte,

Antonios N. Maniatis,

Spyros Pournaras

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm126

Subject(s) - pseudomonas aeruginosa , integron , efflux , microbiology and biotechnology , biology , antibiotics , genetics , antibiotic resistance , bacteria

A Pseudomonas aeruginosa clinical isolate that exhibited high-level carbapenem resistance and produced metallo-beta-lactamase (MBL) was recovered from a Greek patient. This study was conducted to determine the underlying mechanisms that conferred the carbapenem resistance phenotype.

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