Comparative evaluation of VITEK 2® for antimicrobial susceptibility testing of group B Streptococcus
Author(s) -
Asmaa Tazi,
Hélène RéglierPoupet,
Josette Raymond,
J. Adam,
Patrick TrieuCuot,
Claire Poyart
Publication year - 2007
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkm098
Subject(s) - penicillin , microbiology and biotechnology , antibiotics , group b , antibiotic resistance , streptococcus agalactiae , biology , streptococcus , antimicrobial , tetracycline , medicine , bacteria , genetics
Intrapartum antibiotic prophylaxis is recommended to prevent neonatal group B streptococcal (GBS) disease in colonized women, and penicillin or aminopenicillin constitute the first-line antibiotics. Most isolates are resistant to tetracycline, and resistance to macrolide-lincosamide-streptogramin (MLS) antibiotics is increasing. Therefore, laboratory testing for MLS resistance in GBS is now recommended for penicillin-allergic patients. The aim of this study was to compare the antimicrobial susceptibility of GBS as determined by the VITEK 2 system (bioMérieux, Marcy l'Etoile, France), agar diffusion methods and PCR-genotypic detection of resistance genes.
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