Correlation of vancomycin and daptomycin susceptibility in Staphylococcus aureus in reference to accessory gene regulator (agr) polymorphism and function | Zendy

Warren E. Rose | Zendy; Michael J. Rybak | Zendy; Brian T. Tsuji | Zendy; Glenn W. Kaatz | Zendy; George Sakoulas | Zendy

Open Access

Correlation of vancomycin and daptomycin susceptibility in Staphylococcus aureus in reference to accessory gene regulator (agr) polymorphism and function

Author(s) -

Warren E. Rose,

Michael J. Rybak,

Brian T. Tsuji,

Glenn W. Kaatz,

George Sakoulas

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm091

Subject(s) - daptomycin , vancomycin , staphylococcus aureus , microbiology and biotechnology , gentamicin , regulator , antibiotics , biology , gene , medicine , bacteria , genetics

Recently, an association between the accessory gene regulator (agr) in Staphylococcus aureus and the development of vancomycin resistance secondary to suboptimal exposure has been demonstrated. We investigated the relationship of vancomycin with and without gentamicin or rifampicin, and daptomycin in the development of resistance in agr groups I and II.

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