Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis | Zendy

Dharmarajan Sriram | Zendy; Perumal Yogeeswari | Zendy; Murugesan Dinakaran | Zendy; Rathinasababathy Thirumurugan | Zendy

Open Access

Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis

Author(s) -

Dharmarajan Sriram,

Perumal Yogeeswari,

Murugesan Dinakaran,

Rathinasababathy Thirumurugan

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm085

Subject(s) - antimycobacterial , isoniazid , in vivo , mycobacterium tuberculosis , in vitro , tuberculosis , mycobacterium , chemistry , microbiology and biotechnology , multiple drug resistance , pharmacology , biology , medicine , antibiotics , biochemistry , pathology

The objective of this work was to synthesize 15 new 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds and evaluate their in vitro and in vivo antimycobacterial activities.

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