Emergence of the H208Y mutation in the reverse transcriptase (RT) of HIV-1 in association with nucleoside RT inhibitor therapy | Zendy

Gaia Nebbia | Zendy; Caroline Sabin | Zendy; David Dunn | Zendy; Anna María Geretti | Zendy

Open Access

Emergence of the H208Y mutation in the reverse transcriptase (RT) of HIV-1 in association with nucleoside RT inhibitor therapy

Author(s) -

Gaia Nebbia,

Caroline Sabin,

David Dunn,

Anna María Geretti

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm067

Subject(s) - nucleoside reverse transcriptase inhibitor , reverse transcriptase , reverse transcriptase inhibitor , virology , human immunodeficiency virus (hiv) , mutation , medicine , nucleoside , didanosine , antiretroviral therapy , zidovudine , biology , viral disease , genetics , viral load , rna , gene

The aim of the study was to determine whether mutations at RT codon 208 are associated with nucleoside RT inhibitor (NRTI) exposure, NRTI resistance patterns and HIV-1 subtype.

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