No change in calculated creatinine clearance after tenofovir initiation among Thai patients | Zendy

Angèle GayetAgeron | Zendy; Jintanat Ananworanich | Zendy; Thidarat Jupimai | Zendy; Ploenchan Chetchotisakd | Zendy; Wisit Prasithsirikul | Zendy; Sasiwimol Ubolyam | Zendy; Michelle Le Braz | Zendy; Kiat Ruxrungtham | Zendy; James F. Rooney | Zendy; Bernard Hirschel | Zendy

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No change in calculated creatinine clearance after tenofovir initiation among Thai patients

Author(s) -

Angèle GayetAgeron,

Jintanat Ananworanich,

Thidarat Jupimai,

Ploenchan Chetchotisakd,

Wisit Prasithsirikul,

Sasiwimol Ubolyam,

Michelle Le Braz,

Kiat Ruxrungtham,

James F. Rooney,

Bernard Hirschel

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkm064

Subject(s) - renal function , medicine , nephrotoxicity , creatinine , tenofovir , lamivudine , population , urology , ritonavir , human immunodeficiency virus (hiv) , antiretroviral therapy , kidney , viral load , hepatitis b virus , virus , environmental health , family medicine , virology

Thai patients have a lower average body weight than patients from western Europe or the USA. Tenofovir is largely prescribed at the standard dosage of 300 mg once daily: therefore, the per kilogram dose is higher in Thailand than in the USA. We asked the question whether this higher per kilogram dose was associated with more nephrotoxicity.

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