Efficacy of aminocandin in the treatment of immunocompetent mice with haematogenously disseminated fluconazole-resistant candidiasis | Zendy

Mahmoud A. Ghannoum | Zendy; H. G. Kim | Zendy; L. Long | Zendy

Open Access

Efficacy of aminocandin in the treatment of immunocompetent mice with haematogenously disseminated fluconazole-resistant candidiasis

Author(s) -

Mahmoud A. Ghannoum,

H. G. Kim,

L. Long

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl525

Subject(s) - caspofungin , fluconazole , amphotericin b , candida albicans , corpus albicans , echinocandin , pharmacology , medicine , microbiology and biotechnology , mycosis , echinocandins , biology , antifungal , immunology

The objective of this study was to compare the activity of aminocandin, a new echinocandin with broad-spectrum activity against Candida spp., with that of amphotericin B, caspofungin and fluconazole, in an immunocompetent murine model of haematogenously disseminated candidiasis caused by a fluconazole-resistant Candida albicans.

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