Synergistic antimycobacterial activities of sesquiterpene lactones from Laurus spp. | Zendy

Julieta LunaHerrera | Zendy; Maria do Céu Costa | Zendy; H.G. Plascencia GonzÁlez | Zendy; Ana Isabel Rodrigues | Zendy; Paula C. Castilho | Zendy

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Synergistic antimycobacterial activities of sesquiterpene lactones from Laurus spp.

Author(s) -

Julieta LunaHerrera,

Maria do Céu Costa,

H.G. Plascencia GonzÁlez,

Ana Isabel Rodrigues,

Paula C. Castilho

Publication year - 2007

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl523

Subject(s) - antimycobacterial , sesquiterpene , mycobacterium tuberculosis , bioassay , resazurin , chemistry , antibacterial agent , chromatography , biology , stereochemistry , tuberculosis , biochemistry , antibiotics , medicine , pathology , genetics

The aim of this study was to determine the antimycobacterial potential of laurel oil, its fractions and its two sesquiterpene lactones against several mycobacterial strains and clinical isolates, and to establish the possibility of occurrence of some synergistic effects between those lactones using a modification of the fluorometric Alamar Blue microassay (FMABA).

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