Is continuous infusion ceftriaxone better than once-a-day dosing in intensive care? A randomized controlled pilot study
Author(s) -
Jason A. Roberts,
Robert Boots,
Claire M. Rickard,
P. Thomas,
Jennifer A. Quinn,
Darren M. Roberts,
Brent Richards,
Jeffrey Lipman
Publication year - 2006
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkl478
Subject(s) - medicine , ceftriaxone , bolus (digestion) , dosing , odds ratio , confidence interval , randomized controlled trial , intensive care unit , sepsis , intensive care , anesthesia , surgery , antibiotics , intensive care medicine , microbiology and biotechnology , biology
To compare the clinical and bacteriological outcome of critically ill patients with sepsis treated by ceftriaxone administered as a once-a-day intermittent bolus dose or by 24 h continuous infusion.
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