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Ertapenem is a novel carbapenem with activity against both penicillin-susceptible (MIC &lt; or = 0.06 mg/L) and penicillin-non-susceptible (MIC &gt; or = 0.12 mg/L) Streptococcus pneumoniae. This study assessed the pharmacodynamic activity of ertapenem against penicillin-susceptible and penicillin-non-susceptible S. pneumoniae using an in vitro pharmacodynamic model.

Pharmacodynamic activity of ertapenem versus penicillin-susceptible and penicillin-non-susceptible Streptococcus pneumoniae using an in vitro model