Pharmacodynamic activity of ertapenem versus penicillin-susceptible and penicillin-non-susceptible Streptococcus pneumoniae using an in vitro model | Zendy

George G. Zhanel | Zendy; S. Derkatch | Zendy; Nancy M. Laing | Zendy; Ayman Noreddin | Zendy; D. J. Hoban | Zendy

Open Access

Pharmacodynamic activity of ertapenem versus penicillin-susceptible and penicillin-non-susceptible Streptococcus pneumoniae using an in vitro model

Author(s) -

George G. Zhanel,

S. Derkatch,

Nancy M. Laing,

Ayman Noreddin,

D. J. Hoban

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl433

Subject(s) - ertapenem , penicillin , microbiology and biotechnology , streptococcus pneumoniae , minimum inhibitory concentration , antibiotics , antibacterial agent , moxifloxacin , medicine , biology , antibiotic resistance , imipenem

Ertapenem is a novel carbapenem with activity against both penicillin-susceptible (MIC < or = 0.06 mg/L) and penicillin-non-susceptible (MIC > or = 0.12 mg/L) Streptococcus pneumoniae. This study assessed the pharmacodynamic activity of ertapenem against penicillin-susceptible and penicillin-non-susceptible S. pneumoniae using an in vitro pharmacodynamic model.

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