The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus | Zendy

F. W. Goldstein | Zendy

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The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus

Author(s) -

F. W. Goldstein

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl429

Subject(s) - staphylococcus aureus , microbiology and biotechnology , antibiotics , antibiotic resistance , virulence , staphylococcus , in vivo , staphylococcal infections , medicine , biology , bacteria , genetics , gene

Low-level antibiotic resistance in Staphylococcus aureus is a frequently overlooked phenomenon, usually not detected by standard susceptibility testing procedures. It represents a gateway to high-level clinically relevant resistance. Moreover, low-level resistance may be associated with increased virulence, resistance to unrelated compounds and more successful in vivo survival.

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