The combination of ultrasound with antibiotics released from bone cement decreases the viability of planktonic and biofilm bacteria: an in vitro study with clinical strains | Zendy

G.T. Ensing | Zendy; D. Neut | Zendy; Jim R. van Horn | Zendy; H. C. van der Mei | Zendy; Henk J. Busscher | Zendy

Open Access

The combination of ultrasound with antibiotics released from bone cement decreases the viability of planktonic and biofilm bacteria: an in vitro study with clinical strains

Author(s) -

G.T. Ensing,

D. Neut,

Jim R. van Horn,

H. C. van der Mei,

Henk J. Busscher

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl402

Subject(s) - biofilm , microbiology and biotechnology , antibiotics , bacteria , in vitro , chemistry , medicine , biology , biochemistry , genetics

Antibiotic-loaded bone cements are used for the permanent fixation of joint prostheses. Antibiotic-loaded cements significantly decrease the incidence of infection. The objective of this study was to investigate whether the viability of bacteria derived from patients with a prosthesis-related infection could be further decreased when antibiotic release from bone cements was combined with application of pulsed ultrasound.

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