Evaluation of anti-pneumococcal capsular antibodies as adjunctive therapy in experimental pneumococcal meningitis | Zendy

Christian Brandt | Zendy; Niels FrimodtMøller | Zendy; Jens Lundgren | Zendy; Michael Pedersen | Zendy; Ian C. Skovsted | Zendy; Ian J. Rowland | Zendy; Christian Østergaard | Zendy

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Evaluation of anti-pneumococcal capsular antibodies as adjunctive therapy in experimental pneumococcal meningitis

Author(s) -

Christian Brandt,

Niels FrimodtMøller,

Jens Lundgren,

Michael Pedersen,

Ian C. Skovsted,

Ian J. Rowland,

Christian Østergaard

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl401

Subject(s) - streptococcus pneumoniae , meningitis , ceftriaxone , medicine , serotype , antibiotics , concomitant , pneumococcal infections , immunology , bacteremia , antibody , streptococcaceae , microbiology and biotechnology , biology , surgery

Bacteraemia concomitant with meningitis has been shown to greatly affect outcome. Consequently, the efficacy of serotype-specific anti-pneumococcal antiserum (APAS) was investigated in a rat model of pneumococcal meningitis.

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