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High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile
Author(s) -
Denise Drudy,
Teresa Quinn,
Rebecca O’Mahony,
Lorraine Kyne,
Peadar Ó Gaora,
Séamus Fanning
Publication year - 2006
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkl398
Subject(s) - gatifloxacin , clostridium difficile , microbiology and biotechnology , moxifloxacin , toxin , clostridium difficile toxin a , pore forming toxin , clostridium difficile toxin b , clostridiaceae , biology , antibiotics , microbial toxins , levofloxacin
To determine the mechanism of high-level resistance to fluoroquinolone antimicrobials in toxin-A-negative, toxin-B-positive (A- B+) Clostridium difficile isolates.

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