Pharmacokinetic and pharmacodynamic assessment of co-amoxiclav in the treatment of melioidosis
Author(s) -
Wirongrong Chierakul,
Jinda Wangboonskul,
Thida Singtoroj,
Wirichada Pongtavornpinyo,
John M. Short,
Bina Maharjan,
Vanaporn Wuthiekanun,
David A. B. Dance,
Prapit Teparrukkul,
Niklas Lindegårdh,
Sharon J. Peacock,
N. P. Day,
Wipada Chaowagul,
Nicholas J. White
Publication year - 2006
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkl389
Subject(s) - amoxicillin , burkholderia pseudomallei , melioidosis , dosing , pharmacokinetics , medicine , antibacterial agent , pharmacodynamics , antibiotics , dose , clavulanic acid , ceftazidime , pharmacology , microbiology and biotechnology , biology , bacteria , genetics , pathology , pseudomonas aeruginosa
We conducted a prospective pharmacokinetic study of oral co-amoxiclav in patients with melioidosis to determine the optimal dosage and dosing interval in this potentially fatal infection.
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