In vitro activity and synergism of amphotericin B, azoles and cationic antimicrobials against the emerging pathogen Trichoderma spp. | Zendy

Christina Kratzer | Zendy; Selma Tobudic | Zendy; Monika Schmoll | Zendy; W. Graninger | Zendy; A. Georgopoulos | Zendy

Open Access

In vitro activity and synergism of amphotericin B, azoles and cationic antimicrobials against the emerging pathogen Trichoderma spp.

Author(s) -

Christina Kratzer,

Selma Tobudic,

Monika Schmoll,

W. Graninger,

A. Georgopoulos

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl384

Subject(s) - voriconazole , microbiology and biotechnology , trichoderma , amphotericin b , fluconazole , trichoderma harzianum , antagonism , broth microdilution , antimicrobial , azole , chlorhexidine , biology , chemistry , minimum inhibitory concentration , medicine , antifungal , biological pest control , botany , biochemistry , receptor , dentistry

The uncommon fungal pathogen Trichoderma shows increasing medical importance particularly in immunocompromised patients. Despite systemic antifungal therapy, prognosis of Trichoderma infection is poor regardless of the type of infection and the therapy used. The aim of the present study was to evaluate the in vitro activity and synergism of double antifungal combinations including amphotericin B, voriconazole, fluconazole, chlorhexidine digluconate and Akacid plus against 15 isolates of Trichoderma longibrachiatum and 1 isolate of Trichoderma harzianum.

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