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The multidrug efflux pump CmeABC is essential for Campylobacter colonization in animal intestine by mediating bile resistance. The objective of this study is to examine the effect of inhibition of the CmeABC pump by efflux pump inhibitor (EPI) on the susceptibility of Campylobacter to bile salts and to evaluate the in vivo efficacy of two EPIs on the colonization of Campylobacter in a host.

Effect of efflux pump inhibitors on bile resistance and in vivo colonization of Campylobacter jejuni