Effect of efflux pump inhibitors on bile resistance and in vivo colonization of Campylobacter jejuni | Zendy

Jun Lin | Zendy; Aurora Martı́nez | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effect of efflux pump inhibitors on bile resistance and in vivo colonization of Campylobacter jejuni

Author(s) -

Jun Lin,

Aurora Martı́nez

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl374

Subject(s) - campylobacter jejuni , microbiology and biotechnology , efflux , campylobacter , colonization , in vivo , biology , bacteria , biochemistry , genetics

The multidrug efflux pump CmeABC is essential for Campylobacter colonization in animal intestine by mediating bile resistance. The objective of this study is to examine the effect of inhibition of the CmeABC pump by efflux pump inhibitor (EPI) on the susceptibility of Campylobacter to bile salts and to evaluate the in vivo efficacy of two EPIs on the colonization of Campylobacter in a host.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research