Open AccessTigecycline does not induce proliferation or cytotoxin production by epidemic Clostridium difficile strains in a human gut model
Author(s) -
Simon D. Baines,
Katherine Saxton,
Jane Freeman,
Mark H. Wilcox
Publication year - 2006
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkl364
Subject(s) - tigecycline , microbiology and biotechnology , clostridium difficile , biology , antibiotics , bacteroides fragilis
Data on the risk of Clostridium difficile infection (CDI) associated with specific antibiotics are difficult to obtain because of confounding clinical factors. It is particularly important to evaluate the propensity of new antibiotics to induce CDI. We have examined the propensity of tigecycline to induce CDI using a human gut model.
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