pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates from the southeast region of Brazil | Zendy

Patricia Barco | Zendy; Rosilene Fressatti Cardoso | Zendy; Rosário Dominguez Crespo Hirata | Zendy; Clarice Queico Fujimura Leite | Zendy; J. R. C. Pandolfi | Zendy; Daisy Nakamura Sato | Zendy; M L Shikama | Zendy; Fabrício Freire de Melo | Zendy; Elsa Masae Mamizuka | Zendy; Paula Aline Zanetti Campanerut | Zendy; Mário Hiroyuki Hirata | Zendy

Open Access

pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates from the southeast region of Brazil

Author(s) -

Patricia Barco,

Rosilene Fressatti Cardoso,

Rosário Dominguez Crespo Hirata,

Clarice Queico Fujimura Leite,

J. R. C. Pandolfi,

Daisy Nakamura Sato,

M L Shikama,

Fabrício Freire de Melo,

Elsa Masae Mamizuka,

Paula Aline Zanetti Campanerut,

Mário Hiroyuki Hirata

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl363

Subject(s) - pyrazinamide , mycobacterium tuberculosis , microbiology and biotechnology , tuberculosis , biology , antibacterial agent , virology , mutation , gene , medicine , genetics , antibiotics , pathology

To investigate the presence of mutations in the pncA gene in 31 pyrazinamide-resistant Mycobacterium tuberculosis and 5 susceptible strains. MICs and pyrazinamidase (PZase) activity were also determined.

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