Penetration of moxifloxacin into the human pancreas following a single intravenous or oral dose | Zendy

R. Wacke | Zendy; Stefan Förster | Zendy; Ulrich Adam | Zendy; Ralf G. Mundkowski | Zendy; E. Klar | Zendy; UT Hopt | Zendy; Bernd Drewelow | Zendy

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Penetration of moxifloxacin into the human pancreas following a single intravenous or oral dose

Author(s) -

R. Wacke,

Stefan Förster,

Ulrich Adam,

Ralf G. Mundkowski,

E. Klar,

UT Hopt,

Bernd Drewelow

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl353

Subject(s) - moxifloxacin , medicine , penetration (warfare) , pathogenic organism , pharmacology , antibiotics , microbiology and biotechnology , biology , operations research , engineering

Failure to prevent secondary infectious complications in acute necrotizing pancreatitis (ANP) is attributable in part to the limited penetration of antimicrobial drugs. As newer quinolones are particularly attractive owing to their antimicrobial activity, for the first time we studied the penetration of moxifloxacin into pancreatic tissue in patients.

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