Rifampicin/imipenem combination in the treatment of carbapenem-resistant Acinetobacter baumannii infections | Zendy

Mireia Saballs | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Rifampicin/imipenem combination in the treatment of carbapenem-resistant Acinetobacter baumannii infections

Author(s) -

Mireia Saballs

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl274

Subject(s) - imipenem , acinetobacter baumannii , colistin , rifampicin , medicine , carbapenem , antibiotics , microbiology and biotechnology , pneumonia , acinetobacter , ventilator associated pneumonia , bacteremia , tigecycline , pseudomonas aeruginosa , antibiotic resistance , biology , bacteria , genetics

In the setting of a large endemic of Acinetobacter baumannii infections, treatment of those due to carbapenem-resistant strains, susceptible only to colistin, has become a major problem in our hospital during the past years. Successful results have been reported using colistin, but clinical experience with this antibiotic is limited. In our experimental studies using these strains in a mouse pneumonia model, the best results were observed with a combination of rifampicin and imipenem.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research