Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro
Author(s) -
Pisin Chen
Publication year - 2006
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkl227
Subject(s) - mycobacterium tuberculosis , drug , in vitro , tuberculosis , ethylene diamine , diamine , first line , pharmacology , medicine , microbiology and biotechnology , chemistry , biology , biochemistry , pathology , organic chemistry , nuclear chemistry
The purpose of this study was to determine interactions of SQ109, a new asymmetric diamine tuberculosis (TB) drug candidate, with existing antitubercular drugs in vitro and assess its potential to improve combination drug activities against Mycobacterium tuberculosis.
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