Induction of lethal photosensitization in biofilms using a confocal scanning laser as the excitation source | Zendy

Christopher K. Hope | Zendy; Marlene A. Wilson | Zendy

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Induction of lethal photosensitization in biofilms using a confocal scanning laser as the excitation source

Author(s) -

Christopher K. Hope,

Marlene A. Wilson

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl096

Subject(s) - confocal , photosensitizer , biofilm , confocal microscopy , scanning electron microscope , streptococcus pyogenes , fluorescence microscope , microscope , fluorescence , laser , membrane permeability , laser scanning , confocal laser scanning microscopy , materials science , microbiology and biotechnology , chemistry , membrane , biology , optics , bacteria , staphylococcus aureus , pathology , medicine , photochemistry , biochemistry , physics , composite material , genetics

To induce lethal photosensitization in biofilms of Streptococcus pyogenes using the scanning laser in a confocal microscope to photoactivate Sn (IV) chlorin e6 (SnCe6) while simultaneously measuring changes in cell vitality using fluorescent indicators of membrane integrity.

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