Effect of different iodine formulations on the expression and activity of Streptococcus mutans glucosyltransferase and fructosyltransferase in biofilm and planktonic environments | Zendy

Avshalom Tam | Zendy; Moshe Shemesh | Zendy; Uri Wormser | Zendy; Am Sintov | Zendy; Doron Steinberg | Zendy

Open Access

Effect of different iodine formulations on the expression and activity of Streptococcus mutans glucosyltransferase and fructosyltransferase in biofilm and planktonic environments

Author(s) -

Avshalom Tam,

Moshe Shemesh,

Uri Wormser,

Am Sintov,

Doron Steinberg

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl085

Subject(s) - biofilm , glucosyltransferase , streptococcus mutans , iodine , microbiology and biotechnology , bacteria , chemistry , polysaccharide , antibacterial activity , biochemistry , enzyme , biology , genetics , organic chemistry

The glucosyltransferase (GTF) and fructosyltransferase (FTF) enzymes play a pivotal role in dental biofilm formation as they synthesize polysaccharides that act as the extracellular matrix of the biofilm. Iodine is a unique antibacterial agent that has distinct properties from other conventional antibacterial agents. In this study we have examined the effect of iodine and povidone iodine (PI) on gtf and ftf expression in biofilm and planktonic environments and on immobilized and unbound GTF and FTF activity.

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