Evaluation of the nitrate-based colorimetric method for testing the susceptibility of Mycobacterium tuberculosis to streptomycin and ethambutol in liquid cultures
Author(s) -
Heidi Syre,
Håvard Valvatne,
Per Sandven,
Harleen M. S. Grewal
Publication year - 2006
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkl054
Subject(s) - ethambutol , streptomycin , mycobacterium tuberculosis , microbiology and biotechnology , tuberculosis , mycobacterium , nitrate reductase , antibiotics , medicine , biology , chemistry , nitrate , pathology , ecology
To evaluate the inexpensive colorimetric nitrate reductase-based antibiotic susceptibility (CONRAS) assay for testing the susceptibility of Mycobacterium tuberculosis to streptomycin and ethambutol in liquid cultures, and to compare the CONRAS test with the manual mycobacteria growth indicator tube (MGIT) test, using the radiometric BACTEC 460TB method as reference.
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