In vitro acanthamoebicidal activity of a killer monoclonal antibody and a synthetic peptide | Zendy

Pier Luigi Fiori | Zendy; Antonella Mattana | Zendy; Daniele Dessì | Zendy; Stefania Conti | Zendy; Walter Magliani | Zendy; Luciano Polonelli | Zendy

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In vitro acanthamoebicidal activity of a killer monoclonal antibody and a synthetic peptide

Author(s) -

Pier Luigi Fiori,

Antonella Mattana,

Daniele Dessì,

Stefania Conti,

Walter Magliani,

Luciano Polonelli

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl051

Subject(s) - laminarin , monoclonal antibody , glucan , microbiology and biotechnology , in vitro , antimicrobial , receptor , biological activity , biology , toxin , biochemistry , chemistry , antibody , enzyme , immunology

To evaluate the in vitro microbicidal activity against Acanthamoeba castellanii of a murine monoclonal anti-idiotypic antibody (KTmAb) and a synthetic killer mimotope (KP), which mimic a yeast killer toxin (KT) characterized by a wide spectrum of antimicrobial activity through interaction with specific cell wall receptors, mainly constituted by beta-glucans.

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