Open AccessCaspofungin: antifungal activity in vitro, pharmacokinetics, and effects on fungal load and animal survival in neutropenic rats with invasive pulmonary aspergillosis
Author(s) -
Wim van Vianen,
Siem de Marie,
Marian T. ten Kate,
Ron A. A. Mathôt,
Irma A. J. M. BakkerWoudenberg
Publication year - 2006
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkl015
Subject(s) - caspofungin , amphotericin b , aspergillosis , pharmacology , pharmacokinetics , aspergillus fumigatus , echinocandin , echinocandins , biology , microbiology and biotechnology , immunology , antifungal , fluconazole
Evaluation of the potential of caspofungin, in relation to pharmacokinetics, in order to optimize its use in the treatment of filamentous fungal infections.
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