Measurement of ampicillin, vancomycin, linezolid and gentamicin activity against enterococcal biofilms | Zendy

Jonathan Sandoe | Zendy; Joanne Wysome | Zendy; A. West | Zendy; John Heritage | Zendy; Mark H. Wilcox | Zendy

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Measurement of ampicillin, vancomycin, linezolid and gentamicin activity against enterococcal biofilms

Author(s) -

Jonathan Sandoe,

Joanne Wysome,

A. West,

John Heritage,

Mark H. Wilcox

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl013

Subject(s) - gentamicin , linezolid , ampicillin , vancomycin , enterococcus , microbiology and biotechnology , antibiotics , medicine , biofilm , biology , staphylococcus aureus , bacteria , genetics

Enterococci frequently cause biofilm infections but susceptibility of clinical isolates growing in biofilms has not been investigated. The minimum biofilm eradicating concentration (MBEC) has been suggested as a guide to treatment of biofilm infections. We measured an alternative endpoint, the minimum biofilm inhibitory concentration (MBIC) and compared the results with MIC and MBC.

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