Association of antibiotic resistance and higher internalization activity in resistant Helicobacter pylori isolates | Zendy

ChihHo Lai | Zendy; Chun-Hsien Kuo | Zendy; PeiYu Chen | Zendy; SekKwong Poon | Zendy; ChiSen Chang | Zendy; WenChing Wang | Zendy

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Association of antibiotic resistance and higher internalization activity in resistant Helicobacter pylori isolates

Author(s) -

ChihHo Lai,

Chun-Hsien Kuo,

PeiYu Chen,

SekKwong Poon,

ChiSen Chang,

WenChing Wang

Publication year - 2006

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dki479

Subject(s) - helicobacter pylori , internalization , antibiotics , antibiotic resistance , microbiology and biotechnology , drug resistance , persistence (discontinuity) , antibacterial agent , biology , medicine , receptor , geotechnical engineering , engineering

Helicobacter pylori resistance to antibiotics is the main factor for therapy failure, while other features remain largely unknown. The aims of this study are to investigate the relationship of antibiotic resistance and in vitro internalization activity between cure and failure isolates and to determine whether failures are associated with persistence of the same predominant strain.

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