Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli | Zendy

Anja Schumacher | Zendy; Petra Steinke | Zendy; Jürgen A. Bohnert | Zendy; Murat Akova | Zendy; Daniel E Jonas | Zendy; Winfried V. Kern | Zendy

Open Access

Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli

Author(s) -

Anja Schumacher,

Petra Steinke,

Jürgen A. Bohnert,

Murat Akova,

Daniel E Jonas,

Winfried V. Kern

Publication year - 2005

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dki446

Subject(s) - enterobacter aerogenes , microbiology and biotechnology , enterobacteriaceae , efflux , tetracycline , klebsiella pneumoniae , antimicrobial , biology , escherichia coli , multiple drug resistance , citrobacter freundii , drug resistance , antibacterial agent , antibiotics , biochemistry , gene

1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse multidrug resistance (MDR) in Escherichia coli overexpressing RND type efflux pumps, but there is no data on its activity in Enterobacteriaceae other than E. coli.

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