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In vitro activity of a novel compound, the metal ion chelating agent AQ+, against clinical isolates of Staphylococcus aureus
Author(s) -
Benjamin R. D. Short,
Miguel Vargas,
Jonathan C. Thomas,
Simon J. O’Hanlon,
Mark C. Enright
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki428
Subject(s) - staphylococcus aureus , broth microdilution , microbiology and biotechnology , antimicrobial , methicillin resistant staphylococcus aureus , gentamicin , lysis , minimum inhibitory concentration , chemistry , chelation , vancomycin , antibiotics , bacteria , biology , biochemistry , genetics , organic chemistry
To determine the efficacy of a novel antimicrobial compound, AQ+, against a genetically heterogeneous collection comprising 213 Staphylococcus aureus isolates from global sources. AQ+ is an aqueous preparation containing 0.5% 8-hydroxyquinoline.

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