Effect of medium type, age and aeration on the MICs of tigecycline and classical tetracyclines
Author(s) -
Russell Hope,
M. Warner,
Shazad Mushtaq,
M. E. Ward,
Thomas F. Parsons,
David M. Livermore
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki386
Subject(s) - tigecycline , minocycline , agar , microbiology and biotechnology , aeration , antibiotics , medicine , chemistry , biology , bacteria , organic chemistry , genetics
Tigecycline is a minocycline derivative, belonging to a chemical class prone to oxidation and to medium-related effects on susceptibility. We therefore studied the effect of medium type and age on the tigecycline MICs found in broth and on agar by the Clinical Laboratory Standards Institute and British Society for Applied Chemotherapy methods.
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