Staphylococcus aureus small colony variants are resistant to the antimicrobial peptide lactoferricin B
Author(s) -
Ørjan Samuelsen,
Hanne H. Haukland,
Barbara C. Kahl,
Christof von Eiff,
Richard A. Proctor,
Hilde Ulvatne,
Kjersti Sandvik,
Lars H. Vorland
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki385
Subject(s) - microbiology and biotechnology , biology , lysostaphin , staphylococcus aureus , menadione , auxotrophy , peptide , antimicrobial , mutant , bacteria , biochemistry , gene , genetics , enzyme
To determine whether Staphylococcus aureus small colony variants (SCVs) are resistant to the antimicrobial peptide lactoferricin B. To assess if deficiency in transmembrane potential, a common characteristic of SCVs that are haemin- or menadione-auxotrophs, affects the uptake of the peptide into the bacterial cytoplasm.
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