Trends in fluoroquinolone resistance of Mycobacterium tuberculosis complex in a Taiwanese medical centre: 1995–2003 | Zendy

Tsi-Shu Huang | Zendy; Calvin M. Kunin | Zendy; Susan ShinJung Lee | Zendy; Yao-Shen Chen | Zendy; HuiZin Tu | Zendy; Yung-Ching Liu | Zendy

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Trends in fluoroquinolone resistance of Mycobacterium tuberculosis complex in a Taiwanese medical centre: 1995–2003

Author(s) -

Tsi-Shu Huang,

Calvin M. Kunin,

Susan ShinJung Lee,

Yao-Shen Chen,

HuiZin Tu,

Yung-Ching Liu

Publication year - 2005

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dki353

Subject(s) - ofloxacin , levofloxacin , ciprofloxacin , rifampicin , microbiology and biotechnology , mycobacterium tuberculosis , isoniazid , tuberculosis , antibacterial agent , drug resistance , moxifloxacin , multiple drug resistance , antibiotics , medicine , biology , virology , pathology

Fluoroquinolones are being used more frequently for the treatment of multidrug-resistant (MDR) strains of Mycobacterium tuberculosis complex (MTB). This study was designed to determine the frequency of the emergence of fluoroquinolone-resistant strains in Taiwan and to assess whether this might be due to use of fluoroquinolones for treatment of patients with MDR or because of increased use of fluoroquinolones in the community for treatment of other infections. We also sought to determine whether there might be clonal spread of fluoroquinolone resistance.

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