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Anti-metabolic activity of caspofungin against Candida albicans and Candida parapsilosis biofilms
Author(s) -
Christophe Cocuaud,
MarieHélène Rodier,
Gyslaine Daniault,
Christine Imbert
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki269
Subject(s) - caspofungin , microbiology and biotechnology , biofilm , fluconazole , candida albicans , candida parapsilosis , corpus albicans , biology , echinocandins , antifungal , bacteria , genetics
Candidiasis can be associated with the formation of biofilms on bioprosthetic surfaces and the intrinsic resistance of Candida albicans biofilms to the most commonly used antifungal agents has been demonstrated. In this study, we report on the antifungal activity of caspofungin at two different concentrations, on C. albicans and Candida parapsilosis biofilms with different ages of maturation.

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