Open AccessPrediction of resistance to erythromycin in the genus Rickettsia by mutations in L22 ribosomal protein
Author(s) -
JeanMarc Rolain,
Didier Raoult
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki242
Subject(s) - erythromycin , biology , in silico , 23s ribosomal rna , microbiology and biotechnology , rickettsia , ribosomal rna , spotted fever , genetics , virology , antibiotics , gene , ribosome , rna , virus
Typhus group (TG) rickettsiae are naturally susceptible to erythromycin whereas spotted fever group (SFG) rickettsioses are not. The aim of this study was to compare in silico genetic determinants known to be associated with resistance to macrolide compounds.
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