Atazanavir trough plasma concentration monitoring in a cohort of HIV-1-positive individuals receiving highly active antiretroviral therapy
Author(s) -
Alan Winston,
Mark Bloch,
Andrew Carr,
Janaki Amin,
Patrick Mallon,
John E. Ray,
Debbie Marriott,
David A. Cooper,
Sean Emery
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki235
Subject(s) - atazanavir , ritonavir , dosing , medicine , trough concentration , lopinavir , concomitant , pharmacology , nevirapine , therapeutic drug monitoring , pharmacokinetics , viral load , virology , human immunodeficiency virus (hiv) , antiretroviral therapy
Atazanavir is a recently approved HIV protease inhibitor (PI). As with other PIs, careful attention to potential pharmacokinetic drug interactions in clinical practice is necessary. The aim of this study was to assess the clinical associations with plasma atazanavir concentrations in HIV-positive individuals.
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