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Impact of rosiglitazone treatment on the bioavailability of antiretroviral compounds in HIV-positive patients
Author(s) -
Mark Oette,
Michael Kurowski,
Torsten Feldt,
Arne Kroidl,
Abdurrahman Sagir,
C Vogt,
M Wettstein,
Dieter Häussinger
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki234
Subject(s) - cmin , cmax , medicine , nevirapine , rosiglitazone , lopinavir , efavirenz , ritonavir , pharmacology , abacavir , bioavailability , pharmacokinetics , confidence interval , gastroenterology , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy , insulin , immunology
The insulin-sensitizer rosiglitazone is under investigation for therapy of HIV-associated lipodystrophy syndrome (LDS). Little is known about pharmacological interactions with antiretroviral (ARV) drugs.

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