Open AccessColicins prevent colonization of urinary catheters
Author(s) -
Barbara W. Trautner,
R Hull,
Rabih O. Darouiche
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki228
Subject(s) - colicin , microbiology and biotechnology , escherichia coli , bacteriocin , catheter , colonization , urinary system , biology , bacteria , medicine , antimicrobial , surgery , biochemistry , genetics , gene , endocrinology
Natural microbial defence systems, such as bacteriocins, may be a novel means to prevent catheter-associated urinary tract infection. We investigated in vitro whether a colicin-expressing strain of Escherichia coli could prevent urinary catheter colonization by a colicin-susceptible, uropathgenic strain of E. coli.
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