Open AccessBiological consequences of petite mutations in Candida glabrata
Author(s) -
Sophie Brun,
Frédéric Dalle,
Patrick Saulnier,
Gilles Rénier,
Alain Bonnin,
Dominique Chabasse,
JeanPhilippe Bouchara
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki200
Subject(s) - mutant , ethidium bromide , virulence , biology , candida glabrata , microbiology and biotechnology , agarose gel electrophoresis , candida albicans , biochemistry , gene , dna
To define the pathogenicity of respiration-deficient mutants of Candida glabrata, which present a reduced susceptibility to azoles, that are easily induced in vitro by exposure to these drugs or to ethidium bromide and that may be selected in vivo in patients receiving fluconazole.
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