Fluoroquinolone treatment of experimental Salmonella enterica serovar Typhimurium DT104 infections in chickens selects for both gyrA mutations and changes in efflux pump gene expression | Zendy

Luke Randall | Zendy; Deborah J. Eaves | Zendy; S. Cooles | Zendy; Vito Ricci | Zendy; Anthony M. Buckley | Zendy; Martin J. Woodward | Zendy; Laura J. V. Piddock | Zendy

Open Access

Fluoroquinolone treatment of experimental Salmonella enterica serovar Typhimurium DT104 infections in chickens selects for both gyrA mutations and changes in efflux pump gene expression

Author(s) -

Luke Randall,

Deborah J. Eaves,

S. Cooles,

Vito Ricci,

Anthony M. Buckley,

Martin J. Woodward,

Laura J. V. Piddock

Publication year - 2005

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dki189

Subject(s) - enrofloxacin , salmonella enterica , microbiology and biotechnology , nalidixic acid , biology , salmonella , strain (injury) , efflux , antibiotics , campylobacter , tetracycline , bacteria , ciprofloxacin , genetics , anatomy

To determine the efficacy of enrofloxacin (Baytril) in chickens in eradicating three different resistance phenotypes of Salmonella enterica and to examine the resistance mechanisms of resulting mutants.

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