Preservation of topoisomerase genetic sequences during in vivo and in vitro development of high-level resistance to ciprofloxacin in isogenic Stenotrophomonas maltophilia strains | Zendy

Sylvia Valdezate | Zendy; Ana Vindel | Zendy; Juan Antonio Sáez-Nieto | Zendy; Fernando Baquero | Zendy; Rafael Cantón | Zendy

Open Access

Preservation of topoisomerase genetic sequences during in vivo and in vitro development of high-level resistance to ciprofloxacin in isogenic Stenotrophomonas maltophilia strains

Author(s) -

Sylvia Valdezate,

Ana Vindel,

Juan Antonio Sáez-Nieto,

Fernando Baquero,

Rafael Cantón

Publication year - 2005

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dki182

Subject(s) - nalidixic acid , microbiology and biotechnology , stenotrophomonas maltophilia , efflux , biology , ciprofloxacin , mutant , antibacterial agent , quinolone , topoisomerase iv , dna gyrase , antibiotics , bacteria , gene , pseudomonas aeruginosa , genetics , escherichia coli

To ascertain the participation of topoisomerase mutations in the development of ciprofloxacin resistance in isogenic Stenotrophomonas maltophilia mutants.

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