Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol
Author(s) -
Victoria Latham,
Justin Stebbing,
Sundhiya Mandalia,
Christos Michailidis,
Elizabeth Davies,
Mark Bower,
Brian Gazzard,
Mark Nelson
Publication year - 2005
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dki170
Subject(s) - regimen , tenofovir , salvage therapy , virology , medicine , human immunodeficiency virus (hiv) , chemotherapy
Treatment failure during highly active antiretroviral therapy (HAART) is ultimately common and associated with the development of resistance mutations. Trizivir (zidovudine/lamivudine/abacavir) and tenofovir disoproxil fumarate may improve adherence and enhance virological suppression in individuals who have failed previous regimens.
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